What
is meningococcal disease?
What
causes meningococcal disease?
How
many people die from meningococcal disease each year?
How
is meningococcal disease spread?
What
are the symptoms?
Who
is at risk?
How
often do outbreaks occur on college campuses?
Is
one type of serogroup of meningococcal disease more common in college
students?
What
is ACHA's recommendation on meningococcal disease?
Does
the CDC recommend vaccination for college students?
Why
should college students consider preventive vaccination with the
meningococcal vaccine?
Who
should be vaccinated pre-exposure?
Are
colleges and universities following the ACHA recommendation?
How
effective is the vaccine?
Is
the vaccine safe? Are there adverse side effects to the
vaccine?
What
is the duration of protection?
What
is ACHA doing to assess the risk of meningococcal disease among
college students?
What
can a college do if an outbreak occurs?
What is meningococcal disease?
Meningococcal disease is a rare, but potentially fatal
bacterial infection. The disease is expressed as either meningococcal
meningitis, an inflammation of the membranes surrounding the brain
and spinal cord or meningococcemia, the presence of bacteria in the
blood.
What causes meningococcal disease?
Meningococcal disease is caused by the bacterium Neisseria
Meningitidis, a leading cause of meningitis and septicemia (or
blood poisoning) in the United States. Meningitis is one of the most
common manifestations of the disease, although it has been known to
cause septic arthritis, pneumonia, brain inflammation and other syndromes.
How many people die from meningococcal
disease each year?
Meningococcal disease strikes about 3,000 Americans
each year and is responsible for approximately 300 deaths annually.
It is estimated that 100-125 cases of meningococcal disease occur
annually on college campuses and five to 15 students die as a result.
How is meningococcal disease spread?
Meningococcal disease is transmitted through the air
via droplets of respiratory secretions and direct contact with an
infected person. Direct contact, for these purposes, is defined as
oral contact with shared items such as cigarettes and drinking glasses
or through intimate contact such as kissing.
What are the symptoms?
The early symptoms usually associated with meningococcal
disease include fever, severe headache, stiff neck, rash, nausea,
vomiting, and lethargy, and may resemble the flu. Because the disease
progresses rapidly, often in as little as 12 hours, students are urged
to seek medical care immediately if they experience two or more of
these symptoms concurrently.
Who is at risk?
Recent evidence found students residing on campus in
dormitories appear to be at higher risk for meningococcal disease
than college students overall. Further research recently released
by the CDC shows freshmen living in dormitories have a six times
higher risk of meningococcal disease than college students overall.
Although anyone can come in contact with the bacteria
that causes meningococcal disease, data also indicates certain social
behaviors, such as exposure to passive and active smoking, bar patronage,
and excessive alcohol consumption, may put students at increased risk
for the disease. Patients with respiratory infections,compromised
immunity, those in close contact to a known cause, and travelers to
epidemic area of the world are also at increased risk. Cases and outbreaks
usually occur in the late winter and early spring when school is in
session.
How often do outbreaks occur on college
campuses?
From 1980 to 1993, there were 21 outbreaks, three of
which occurred in colleges. From 1994 to 1996, there have been 51
outbreaks, six of which occurred in colleges. Between 1986 and 1993,
an outbreak was defined as five cases of the same serotype in 100,000
people with at least three occurring within three months. From 1994
to present, 10 cases of the same serotype in 100,000 people with at
least three occurring within three months constitute an outbreak.
Is one type of serogroup of meningococcal
disease more common in college students?
Recent evidence shows the epidemiology of meningococcal
disease is changing with a majority of cases (65 percent) in the college
age group caused by either serotype C, Y, or W-135, which are all
vaccine preventable.
What is ACHA's recommendation on meningococcal
disease?
ACHA Vaccine-Preventable Disease Task Force has agreed
to adopt the new ACIP recommendation, which recommends that undergraduate
college students, particularly freshmen who live in or plan to live
in dormitories or residence halls, consider getting the vaccine to
reduce their risk for meningococcal disease.
Does the CDC recommend vaccination for college
students?
As of October 20, 1999, the advisory Committee on Immunization
Practices (ACIP) of the U.S. Centers for Disease Control and Prevention
(CDC) recommends that individual who provide medical care to college
freshmen, particularly those who live in or plan to live in dormitories
or residence halls, should provide information about meningococcal
disease and the benefits of vaccination with these students and their
parents. ACIP further recommends that immunization should be provided
or made easily available to those who wish to reduce their risk for
meningococcal disease. Other undergraduate students wishing to reduce
their risk for meningococcal disease can also choose to be vaccinated.
Additionally, the ACIP recommends that college and universities
provide information about meningococcal disease and the vaccine to
freshman, particularly those who plan to live in dormitories and residence
halls, and encourage public health agencies to serve as a resource
for information about meningococcal disease and vaccination, including
how to obtain the vaccine.
Why should college students consider preventative
vaccination with the meningoccocal vaccine?
Data from the U.S. Centers for Disease Control and
Prevention (CDC) demonstrate increasing incidence of outbreaks on
college campuses. Data further suggests that sub-populations of college
students are at increased risk for meningococcal disease. Pre-exposure
vaccination enhances immunity to four strains of meninococcus that
cause 65-70% of invasive disease and therefore reduces a student's
risk for disease. Development of immunity post-vaccination requires
7-10 days.
Who should be vaccinated pre-exposure?
Are colleges and universities following
the ACHA recommendation?
Since the release of ACHA's recommendation in 1997,
it is estimated that as many as 200 colleges and universities have
included the ACHA recommendation on their college entrance health
forms and/or conducting awareness campaigns to educate parents and
college students about this disease.
How effective is the vaccine?
The meningococcal vaccine has been shown to provide
protection against the most common strains of the disease, including
serogroups A, C, Y, and W-135. The vaccine has shown to be 80-100%
effective in serogroups A and C in young adults.
Is the vaccine safe? Are there adverse
side effects to the vaccine?
The vaccine is very safe and adverse reactions are
mild and infrequent, consisting primarily of redness and pain at the
site of the injection lasting up to two days.
What is the duration of protection?
The duration of the meningococcal vaccine's efficacy
is approximately three to five years.
What is ACHA doing to assess the risk
of meningococcal disease among college students?
ACHA is currently partnering with the CDC on a surveillance
study to identify potential subgroups of college students that may
be at increased risk for meningococcal disease. Results of this study
will be published in the near future.
What can a college do to protect students
if an outbreak occurs?
If a suspected or diagnosed case of meningococcal meningitis
is reported (on campus or in neighboring communities), the following
intervention measures should be considered:
Because meningitis is one of the most feared diagnoses in the U.S.,
sporadic cases and outbreaks almost invariably spread panic through
college communities. In order to proactively guard against an outbreak
(or endemic disease), ACIP recommends that undergraduate college students,
particularly freshmen who live in or plan to live in dormitories or
residence halls, should shoulder getting the vaccine.
In the event of an actual meningitis outbreak, ACHA has developed a
response kit to guide college health officials in appropriately and
expeditiously responding to sporadic cases and outbreaks. For more information
about the kit, e-mail ACHA.