Strother began her teaching career in Baltimore Maryland at The Institute of Notre Dame. She and her husband Bob moved to Greenville in 1974 to work for the Greenville County School District. It was during her tenure with the district that Strother had the opportunity to experience teaching children at all grade levels, including kindergarten through grade twelve. Strother was named Secondary Art Educator of the Year by the South Carolina Art Education Association in 1982, and in 1986 she was selected Teacher of the Year by her colleagues at Wade Hampton High School. Strother has served as an assessment specialist for the College Board's Advanced Placement Studio Art Program and for the National Board for Professional Teaching Standards. Strother has been recognized for her accomplishments in Who's Who Among America's Teachers. In 2003 Strother began teaching courses in Art Education and Book Arts at Furman University.
Strother has been a professional bookbinder and restorer of Bibles and fine books for the past 30 years. Her hand bindery under the name of Strother Bookbinding is located in Greenville.